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KMID : 0931320140140040225
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대한상부위장관.헬리코박터학회지
2014 Volume.14 No. 4 p.225 ~ p.232
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Helicobacter pylori Infection and Food Intervention for Preventing Associated GastricDiseases Including Gastric Cancer
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Chung Mi-Kyung
Kim Hye-Sung
Park Jong-Min
Kim Eun-Hee
Han Young-Min
Kwon Sung-Hun
Park Kun-Young
Hahm Ki-Baik
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Abstract
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Since the discovery of Helicobacter pylori infection as the major cause of gastroduodenal disorders including acute and chronic gastritis,gastroduodenal ulcer, chronic atrophic gastritis, and gastric malignancy almost three decades ago, the possibility of preventingthese clinical diseases through eradication has been the focus of active research and debate, especially since eradication can preventcancer. Eradication intervenes with the initiation and progression of mucosal atrophy, metaplasia, dysplasia and gastric cancer. Ourgroup hypothesized that nutritional interventions can rejuvenate the atrophic mucosa and ameliorate H. pylori-associated gastricinflammation. In this review article, the experience and outcomes regarding nutritional applications to rejuvenate gastric atrophywill be introduced. Korean red ginseng, garlic extracts, cancer preventive Korea Kimchi, n-3 polyunsaturated fatty acids, specialform of licorice, and probiotics will be reviewed. The detailed effects of dietary and bacterial eradication therapy on disease progressionand lesion reversibility are discussed.
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KEYWORD
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Helicobacter pylori, Gastritis, Rejuvenation, Carcinogenesis, Prevention & control
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